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Providing new treatment options for facial wrinkles and folds, Galderma has recently released two new FDA-approved Restylane® injections: Restylane® Refyne and Restylane® Defyne. Maryland Dermatology Laser Skin & Vein is pleased to be adding these treatments to our injection options.

The latest hyaluronic acid dermal fillers approved by the FDA, Restylane Refyne and Restylane Defyne emphasize smoother, natural-looking results for the face. Both are manufactured with what’s called XpresHAn Technology, which lets the hyaluronic acid gel move with a patient’s skin as his or her facial muscles move.

Restylane Refyne can treat moderate to severe facial wrinkles and folds, and Restylane Defyne can treat moderate to severe deep facial wrinkles and folds. Results from both of these treatments have been shown to last for up to 12 months in patients. For individuals looking for a better, more natural-looking way to treat facial lines and wrinkles, please contact our office to see if these new injectables are right for you.

Watch Dr. Margaret Weiss perform a live Restylane Defyne treatment

Restylane Defyne, Refyne, and Contour Before and After

*Results may vary for each patient.

Restylane Defyne, Refyne, and Contour Testimonial

I am writing to tell you how thrilled I am with the results of my Restylane filler. I was quite nervous about the procedure and you were wonderful – you told me what I needed and proceeded with a calm that made me relax & feel confident that I was in the “right hands”! Everyone I came into contact with was pleasant. Thank you all for making my experience so positive.


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